KPV (α-MSH fragment)

Description

Silent the Signal. Target Inflammation at Its Core.

KPV (Lys-Pro-Val) is a tripeptide fragment of the alpha-melanocyte-stimulating hormone (α-MSH), known for its potent anti-inflammatory and immunomodulatory properties without triggering systemic hormonal effects.

Unlike full-length α-MSH, KPV isolates the core anti-inflammatory sequence, allowing researchers to focus on its effects in gut integrity, skin inflammation, and immune response models—with minimal receptor cross-talk.

In research, KPV is used to investigate:

⚡️ TNF-α and NF-κB pathway suppression
⚡️ Gut barrier protection and colitis models
⚡️ Skin inflammation, wound healing, and antimicrobial activity
⚡️ Immune modulation without systemic endocrine disruption

KPV’s small size and selective action make it a unique tool for labs studying local inflammation, epithelial repair, and autoimmune signaling—especially where subtle, localized responses matter.

Product Details:

Synonyms: KPV Tripeptide, α-MSH(11–13)

CAS Number: 40077-57-4

Molecular Formula: C17H31N5O4

Molecular Weight: 369.46 g/mol

Form: Lyophilized powder (Receptor Grade)

Storage: Store in a cool, dry place. Refrigerate or freeze for long-term stability. Avoid repeated freeze-thaw cycles.

⚠️ Research Use Only

KPV is sold strictly for laboratory research use only. It is not for human use, cosmetic application, or therapeutic treatment. This product is not FDA-approved and is not intended to diagnose, treat, cure, or prevent any disease. By purchasing, you confirm you are a qualified researcher or laboratory professional using it under applicable laws.